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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
35.76
Human Site:
S130
Identified Species:
56.19
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
S130
E
I
E
D
L
F
S
S
L
K
H
I
Q
H
T
Chimpanzee
Pan troglodytes
XP_510014
764
85553
S219
E
I
E
D
L
F
S
S
L
K
H
I
Q
H
T
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
S130
E
I
E
D
L
F
S
S
L
K
H
I
Q
H
T
Dog
Lupus familis
XP_547862
675
77214
S130
E
V
E
D
L
F
S
S
L
K
H
I
Q
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
S130
D
V
E
D
L
F
S
S
L
K
H
I
Q
H
T
Rat
Rattus norvegicus
Q5U2Y3
576
65604
V110
N
V
K
A
L
L
S
V
H
D
T
V
A
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
S130
E
V
E
D
L
F
S
S
L
K
H
I
Q
H
T
Chicken
Gallus gallus
Q5ZJ00
468
52501
Frog
Xenopus laevis
NP_001085267
675
76810
S130
E
I
E
D
L
L
S
S
L
K
D
I
Q
H
T
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S131
E
L
E
D
L
L
M
S
L
K
Q
V
Q
H
S
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
Fruit Fly
Dros. melanogaster
Q24210
898
100893
T324
N
M
D
P
L
Y
A
T
D
A
D
M
P
I
T
Honey Bee
Apis mellifera
XP_393395
1033
115664
E462
S
G
P
G
V
E
A
E
L
E
A
V
R
T
L
Nematode Worm
Caenorhab. elegans
P54936
961
108794
P162
A
S
K
D
T
S
A
P
L
K
L
C
G
F
G
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
T427
D
L
Q
D
L
L
T
T
L
S
L
A
Q
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
93.3
0
86.6
60
0
13.3
6.6
20
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
0
86.6
80
0
53.3
40
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
20
0
0
7
7
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
14
0
7
67
0
0
0
0
7
7
14
0
0
0
0
% D
% Glu:
47
0
54
0
0
7
0
7
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
40
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
40
0
0
54
0
% H
% Ile:
0
27
0
0
0
0
0
0
0
0
0
47
0
7
0
% I
% Lys:
0
0
14
0
0
0
0
0
0
60
0
0
0
0
14
% K
% Leu:
0
14
0
0
74
27
0
0
74
0
14
0
0
0
7
% L
% Met:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
7
7
0
0
0
7
0
0
0
0
7
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
7
0
60
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
7
0
0
0
7
54
54
0
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
7
0
7
14
0
0
7
0
0
7
54
% T
% Val:
0
27
0
0
7
0
0
7
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _